• Knowledge about adipose tissue has evolved considerably over

  2024-05-29

  

  Knowledge about adipose tissue has evolved considerably over the last two decades. Always been described as an inert tissue having the function of stocking lipids, adipose tissue is now recognized as a real organ with both metabolic and endocrine functions secreting various factors into the blood to

• The first objective of the present study

  2024-05-29

  

  The first objective of the present study was to investigate the impact of ageing on arginase activity in tissues which exhibit age-related impairments in their function. The second objective was to determine whether l-arginine supplementation modulated the effect of ageing on arginase activity. The

• br Materials and methods br Results br Discussion In this

  2024-05-29

  

  Materials and methods Results Discussion In this study, we administrated BDE-153 to newborn rat pups at PND 10 and cultured primary neurons, measured neuronal apoptosis and LDH activity in vivo and in vitro, then explored the possible predominant pathway underlying the neuronal apoptosis by

• At Johns Hopkins Aramco Health JHAH

  2024-05-29

  

  At Johns Hopkins Aramco Health (JHAH), we started an ASP in 2011 with an educational program of physicians and pharmacist. The program was enhanced mid-2012 with the following interventions: a re-designed antibiotic sensitivity report [2], intravenous to oral conversion program, vancomycin pharmacok

• A-803467 Introduction Inflammasomes are large cytosolic prot

  2024-05-28

  

  Introduction Inflammasomes are large cytosolic protein complexes with multiple components that trigger a rapid immune response against pathogen-associated molecular pattern A-803467 (PAMPs) during pathogen infections or damage-associated molecular pattern molecules (DAMPs) during tissue damage [1]

• We have previously shown that the human gonadotropins

  2024-05-28

  

  We have previously shown that the human gonadotropins hLH and hCG trigger a partly irreversible stimulation of intracellular cyclic AMP accumulation in mouse Leydig Tumor retinoid x receptor (MLTC) in contrast to all other tested mammalian LHs and CG (Klett et al., 2016). In order to get a better i

• br Acknowledgements This work was

  2024-05-28

  

  Acknowledgements This work was supported by Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (FAPERGS) FINEP research grant “Rede Instituto Brasil

• During years research efforts at Los Alamos

  2024-05-28

  

  During 2002–2004years research efforts at Los Alamos National Laboratory (LANL) focused on constructing a quantum computer based on regular arrays build from neutral radical molecules possessing one single unpaired MK-2048 spin. The idea was built on the ability to manipulate individual electron spi

• Mistletoe is universal name for various species of

  2024-05-28

  

  Mistletoe is universal name for various species of parasitic plant which grows attached to and within the branches of host trees such as apple, elm, oak and pine. Mistletoe extract prepared from Viscum album, a species of mistletoe in the family Santalaceae, is generally known as European mistletoe

• In plants altered expression of Aurora

  2024-05-28

  

  In plants, altered expression of Aurora kinases results in impaired meiotic divisions followed by the formation of aneuploid or polyploid progenies [21]. This observation is interesting from an evolutionary point of view because it can be assumed that, during evolution, the influence of biotic and a

• To investigate if WP increased

  2024-05-27

  

  To investigate if WP increased CAT activity in cells, C2C12 muscle Zinc Pyrithione were treated with 0.1 to 0.4 mg/mL of WP (80.05% protein) for 24 h and then stressed with 0.75 mM H2O2 for 1 h (Xu et al., 2011). The CAT activity was significantly enhanced from 15.1 ± 0.7 to 23.7 ± 1.3 U/mg of tota

• Natural compounds present in medicinal and or

  2024-05-27

  

  Natural compounds, present in medicinal and/or nutritional plants as well as in macrofungi sources, have stimulated a great interest from the pharmaceutical industry. Different natural compounds such as phenolic compounds, alkaloids, terpenoids among others, have shown strong antiangiogenic effects

• br Materials and methods br Results br Discussion Endophilin

  2024-05-27

  

  Materials and methods Results Discussion Endophilin A1 is a membrane-binding protein that is mainly distributed in the central nervous system (Giachino et al., 1997), localizes in the dendritic shafts and spines of mature neurons (Yang et al., 2015), and relates to the function and morpholo

• Cell surface metalloproteases coordinate signaling

  2024-05-27

  

  Cell surface metalloproteases coordinate signaling during development, tissue homeostasis, and disease. A disintegrin and metalloprotease 17 (ADAM17) is a well-characterized member among ADAM family, which mediates the cleavage of various cell surface proteins (Black, 2002, Black et al., 1997, Dello

• br Available treatment modalities for individuals with NAFLD

  2024-05-27

  

  Available treatment modalities for individuals with NAFLD There are several treatment modalities currently used or in clinical trials for individuals with NAFLD. The most widely recommended treatment is a lifestyle modification plan. As little as 5% weight loss has been shown to improve NASH hist

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