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In patients who develop bone metastases these are
2019-05-14
In patients who develop bone metastases, these are commonly diagnosed at the time of their initial work up for their metastatic disease (∼80%) [7], although others can develop skeletal metastases at any time during the disease course. The consequences of bone metastases include pain (∼80%) [3,6,8] a
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At the mechanistic level our
2019-05-14
At the mechanistic level, our results strongly suggested that the cholestatic protective effect of STS was most likely accounted for by the activation of LXR, a nuclear receptor known for its anti-cholestatic activity. The activation of LXR was supported by the induction of typical LXR target genes,
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La Coordinadora entiende como imposible
2019-05-14
La Coordinadora entiende como imposible la reconstrucción de su pueblo sin el territorio, sin el control territorial. Debemos recordar que en el pensamiento de la cam, la memoria del agravio hace legítima su visión de despojo y el reconocimiento que, en su momento, los mapuches tuvieron, que implicó
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γ-Secretase inhibitor IX El tenor de aquella declaratoria
2019-05-14
El tenor de aquella declaratoria se escribió con estas palabras: De este modo, y al margen de otras consideraciones que pudieran hacerse al respecto, para el caso que nos ocupa es importante significar que la iniciativa mexicana acabó tapiando las puertas de la onu γ-Secretase inhibitor IX la Españ
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br Current approaches to HIV prevention typically target
2019-05-13
Current approaches to HIV prevention typically target people who are identified as, or self-identify, with being at risk. In Africa, 74% of new HIV infections are among adolescent girls aged 15–19 years, and AIDS-related illnesses are the leading cause of death among adolescent girls and women of
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In this study all tumors were Campanacci stage which is
2019-05-13
In this study, all tumors were Campanacci stage 3, which is a significantly higher proportion than in our database [9]. Such a high stage usually suggests that a tumor is highly aggressive and may be a high-risk factor for lung metastasis. Previous reports have also suggested that the stage of a GCT
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ERS and BrS are thought to
2019-05-13
ERS and BrS are thought to represent 2 manifestations of the JWSs. Both syndromes are associated with vulnerability to development of polymorphic VT and VF leading to SCD [1–3,15] in young adults with no apparent structural aa utp disease and occasionally to sudden infant death syndrome [25–27]. The
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br En el ciclo de novelas que de una forma
2019-05-13
En el ciclo de novelas que de una forma u otra giran alrededor de la violencia y del narcotráfico, Cóbraselo caro atraviesa todos esos textos para preguntarse, por un lado, por la génesis de la violencia mexicana y por otro, para manifestar el deseo de una limpieza hallada en el modelo de mundo de
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rsv virus As la historia a la vez ejemplar e ilustrativa
2019-05-13
Así, la historia, a la vez ejemplar e ilustrativa, es un elemento aglutinador de la identidad del pueblo mexicano pues conforma la narración unificadora necesaria para fusionar, en una identidad única, a la sociedad mexicana. Por ello, para Vigil, la enseñanza de la historia convertiría “a los habit
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With the publication of this month s issue we mark
2019-05-13
With the publication of this month\'s issue, we mark \'s first birthday. I hope you will allow me to effuse for a moment in the manner of a new parent discovering the fascination of her offspring\'s everyday achievements… Since its conception in March, 2013, the infant has maintained a healthy int
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Estos cuatro momentos expresan los pasos
2019-05-13
Estos cuatro momentos expresan los pasos más importantes del desprendimiento de la crítica y la práctica literaria en relación con la política partidista. Es decir, son tomas de posición estético-literarias que abrigan en su interior tomas de posición política que, niclosamide la postre, socavan los
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LY2584702 To overcome these resistance mechanisms in APL cel
2019-05-13
To overcome these resistance mechanisms in APL cells, a number of drugs have been tested. Tamibarotene is approximately 10 times more potent than ATRA as an in vitro inducer of differentiation, and is chemically more stable than ATRA [5]. Although the precise mechanism of the combination of tamibaro
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A Cochrane review retained the three
2019-05-13
A 2015 Cochrane review retained the three community-based studies mentioned above and concluded that there was high-quality evidence of reduced risk of infection or omphalitis and death. The review also included two studies in which chlorhexidine was applied in a hospital setting: the above-describe
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In a study of the atrial pacing
2019-05-13
In a study of the atrial pacing preference (APP) algorithm, Ogawa et al. [12] randomly programmed pacemakers as APP OFF and APP ON at 3 different settings (8, 16, and 33 cycles). The authors found that the most effective setting differed according to the patient and thus concluded that this therapy
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order Fmoc-His(Trt)-OH br Diagnostic criteria Brugada syndro
2019-05-13
Diagnostic criteria Brugada syndrome is definitively diagnosed when a type-1 ST-segment elevation is observed in at least 1 right precordial lead (V1 and V2) [23], placed in a standard or a superior position (up to the second intercostal space) (Fig. 1C) [24,25], in the presence or absence of a s
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