• br Methods The Spanish GEM MAS trial lasted

  2019-06-14

  

  Methods The Spanish GEM05MAS65 trial lasted from March, 2006 to October, 2008 and included 260 patients from 63 Spanish centers. At study entry, every patient was aged 65 years or older and had newly diagnosed, untreated, symptomatic, measurable MM. These patients had received a homogeneous induc

• simvastin br La flor de Coleridge En el ensayo de

  2019-06-13

  

  La flor de Coleridge En el ensayo de ese nombre contenido en Otras inquisiciones leemos: De inmediato, y como corolario de estas ideas, nuestro ensayista da un salto para instalarnos en un mundo donde esta probabilidad se cumple: Como en el universo de Tlön, y siguiendo las premisas del idealis

• br As one of the few

  2019-06-13

  

  As one of the few countries that have achieved Millennium Development Goals 4 and 5, China has had a remarkable decline in under-5 mortality rate in past three decades. Drivers of such rapid improvement in China have been widely discussed. In , Chunhua He and colleagues report a decline in under-

• br Conclusions Implantable monitoring devices have become hi

  2019-06-13

  

  Conclusions Implantable monitoring devices have become highly useful diagnostic tools for AT/AF [32]. However, the accuracy of the obtained diagnostic information is influenced by several factors, including the presence of non-AT/AF events, such as RNRVAS or PMT, caused by VA conduction or by sub

• One day post implant the chest X ray showed the

  2019-06-13

  

  One day post-implant, the chest X-ray showed the pacemaker lead in place within the RV (Fig. 1b, thick white arrow) with appropriate slack (thin black arrow). The pacemaker parameters were satisfactory and the patient was discharged home on the same day. Two weeks after implantation, after returnin

• HCV does not kill the cells it

  2019-06-13

  

  HCV does not kill the 2b3a inhibitors it infects, but triggers an immune-mediated inflammatory response (hepatitis) that either rapidly clears the infection or slowly destroys the liver, causing the development of HCC and cirrhosis. The outcome is largely determined by the efficiency of the antivir

• The tumor microenvironment is enriched with EMVs that

  2019-06-13

  

  The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma

• La pol tica institucionalizada se convirti

  2019-06-13

  

  La política institucionalizada se convirtió y se aceptó, por parte de los actores relevantes del sistema (neo-oligarquías e instituciones), y en gran medida por lo benevolente y bondadosa que sería para los intereses del gran capital, como el vehículo hacia el futuro del Estado. Se decretó que la cr

• Despu s de mucho tiempo Argentina dio una respuesta positiva

  2019-06-13

  

  Después de mucho tiempo, Argentina dio una respuesta positiva a la decisión política, tanto de Colombia como de Perú, de reactivar las relaciones bilaterales. En cambio, en el nexo con Chile, Argentina no tenía que dar respuestas sino buscar alternativas para tratar de salir del progresivo debilitam

• Los gobiernos actuales de Bolivia

  2019-06-13

  

  Los gobiernos actuales de Bolivia y Ecuador, que fueron activos impulsores de los cambios constitucionales, tienen entonces simultáneamente el mandato de aprovechar (en Bolivia incluso de industrializar) los recursos naturales y de proteger los derechos de la naturaleza y los derechos de los pueblos

• dpp-4 inhibitors br The world population faces various types

  2019-06-13

  

  The world population faces various types of climate-related hazards, and both the frequency and intensity of hazards are projected to increase in the future because of climate change. Since climate change could increase human health risks, many previous studies first estimated future temperatures

• Sephin1 Cardiac fibroblasts express various ion channels in

  2019-06-12

  

  Cardiac fibroblasts express various ion channels, in particular voltage-gated K Sephin1 and nonselective cation channels of the transient receptor potential (TRP) family . Both K and TRP channels are important determinants of fibroblast function, with TRP channels acting as Ca entry pathways that s

• br Discussion Over the past two decades the incidence of

  2019-06-12

  

  Discussion Over the past two decades, the incidence of second primary malignancy has progressively risen among cancer survivors and is an issue of increasingly greater concern in oncology. The increasing incidence may be due to the elevated rate of early cancer detection, improved cancer treatmen

• Introduction Acute erythroleukemia AEL is a

  2019-06-12

  

  Introduction Acute erythroleukemia (AEL) is a rare subtype of acute myeloid leukemia (AML), accounting for 3–5% of all AML cases. It is characterized by the expansion of erythroblasts in the bone marrow (BM). Its clinical presentation often resembles myelodysplastic syndromes (MDS), both in terms o

• The recently published global consensus recommendations on p

  2019-06-12

  

  The recently published global consensus recommendations on prevention and management of rickets advocate for the eradication of rickets and osteomalacia through implementation of national supplementation and food fortification programmes containing vitamin D, calcium, or both. On the basis of high-q

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