• Two other groups subsequently published further data on iPSC

  2019-06-18

  

  Two other groups subsequently published further data on iPSCs models of ARVC that have improved our understanding of this disease. Kim et al. developed iPSC models using episomal methods from 2 ARVC patients, as well as with PKP2 mutations . Detailed electrophysiological characterization of mutant a

• br Epidemiology Electrophysiological BrS phenotypes

  2019-06-17

  

  Epidemiology Electrophysiological BrS phenotypes occur predominantly in young male adults ( by (±)-Anatoxin A fumarate rate, autonomic nervous system activity, some types of drugs, and a febrile state. Therefore, the true prevalence of BrS in the general population is difficult to estimate. Howev

• br Discussion Sato et al first reported TCM

  2019-06-17

  

  Discussion Sato et al. [11] first reported TCM in 1990, and thereafter, numerous cases were reported in the late 2000s. In 85% of the cases, TCM onset was preceded by an emotional or physical stress event, however, in 15% of the cases, the presence of a stress trigger could not be detected [2]. M

• br Discussion Prehabilitation is a program to enhance functi

  2019-06-17

  

  Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, and

• br As the only methods

  2019-06-17

  

  As the only methods available for dual protection against pregnancy and sexually transmitted infections (STIs), male and female condoms have a vital role in sexual and reproductive health. Mags Beksinska and colleagues therefore are to be commended for their randomised crossover trial in this N-a

• br Materials and methods br Results and discussion ABT is

  2019-06-17

  

  Materials and methods Results and discussion ABT-737 is a BH3-mimetic targeting Bcl-2, Bcl-XL and Bcl-W. The aim of the experiments was to test whether inhibition of Bcl-2 and Bcl-XL using ABT-737 can eradicate the CD34+/CD38− AML cell population. Bone marrow MNCs from patients (Table 1) were

• br Update on the diagnosis of

  2019-06-17

  

  Update on the diagnosis of ERS ERS is generally diagnosed in patients who display ER in the inferior and/or lateral leads presenting with aborted cardiac arrest, documented VF, or polymorphic VT. Consistent with the recent consensus report on ERP [24], ER is recognized if (1) there is an end QRS

• br Conclusions br Disclosures br Funding Sources br Introduc

  2019-06-17

  

  Conclusions Disclosures Funding Sources Introduction Pulmonary vein isolation (PVI) has become an accepted treatment for atrial fibrillation (AF) [1]. The efficacy of PVI is sometimes insufficient, and atrial substrate modification of target specific AF signals indicating the substrate r

• br Descripci n de las variantes

  2019-06-17

  

  Descripción de las variantes Las variantes en los dos poemas estudiados a veces son leves: puntuación, acentuación o actualización de la ortografía. Pero cuando las acotaciones implican cambio de léxico o la sustitución de una parte o de un verso completo, constituyen un problema textual que ayud

• br Grant support This work was supported

  2019-06-15

  

  Grant support This work was supported by INSERM, the “Ligue Contre le Cancer” (Equipe Labellisée LIGUE 2012; grant EL2012NCC/DH), the “Fédération Nationale Enfants et Santé” and the “Société Française de lutte contre les Cancers et les leucémies de l\'Enfant et de l\'Adolescent(“appel à projet 20

• br Reflexiones finales En el presente art culo hemos

  2019-06-15

  

  Reflexiones finales En el presente artículo hemos analizado a la Virgen de caacupé como proceso de construcción social identitaria. para ello hemos abordado el traslado y refundación de la devoción por parte de los migrantes paraguayos a la ciudad de San carlos de Bariloche. este proceso en tanto

• br Materials and methods Eculizumab levels were measured at

  2019-06-15

  

  Materials and methods Eculizumab levels were measured at Cambridge Biomedical using a manual ELISA method in which the microtitre plates are coated with C5, then blocked. Standards, controls, and unknowns were added. After incubation and washing, mouse anti-human IgG4 horseradish peroxidase (HRP)

• As Table shows all guidelines recommend

  2019-06-15

  

  As Table 2 shows, all guidelines recommend OACs for patients with a CHADS2 score of ≥2, whereas recommendations for low-risk patients with a CHADS2 score of 0/1 differ slightly across guidelines. Evidence indicating that novel OACs decrease the risk of ICH by half as compared with warfarin has affec

• The following is the Supplementary material related to this

  2019-06-15

  

  The following is the Supplementary material related to this article Video 1, Video 2, Video 3. Discussion In the electrophysiology setting, increased pericardial effusion or tamponade risk is associated with left-sided arrhythmia ablations, biventricular pacemaker placements, and implantable car

• br Genetic basis for atrial

  2019-06-15

  

  Genetic basis for atrial standstill Genetic basis of conduction block Genes involved in cardiac development and bradycardia Development of the CCS is a complex biological process with the potential to be wrought with problems. Several transcription factors, including homeodomain proteins an

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