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br An understanding of the global health
2019-06-21
An understanding of the global health burden of sex work, including sex trafficking and transactional sex, is urgently needed to direct resources to very large and vulnerable populations. Estimation of this burden will be a challenge, but similar efforts have been undertaken in other populations a
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Vollmer and colleagues distinctive multilevel modelling has
2019-06-21
Vollmer and colleagues\' distinctive multilevel modelling has potential weaknesses that warrant further investigation. The authors imply that tremendous statistical power is derived from the availability of Demographic and Health Survey data for about 460 000 children and their households. But becau
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Si bien con menor despliegue una atenci n
2019-06-21
Si bien con menor despliegue, una atención parecida puede rastrearse en otros protagonistas de la emancipación o en sus enemigos. Como en el caso de Miranda, numerosos personajes mostraron curiosidad por el mundo antiguo y al mismo tiempo sus lecturas revelan que el interés era satisfecho por obras
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In the APHRS survey most respondents answered that OACs
2019-06-20
In the APHRS survey, most respondents (86%) answered that OACs were discontinued before endoscopy or surgery. With novel OACs, physicians will be able to discontinue anticoagulant therapy before the surgical procedure without concern for thrombotic complications. The APHRS survey did not investigate
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Chronic myelomonocytic leukemia has been reported as the mos
2019-06-20
Chronic myelomonocytic leukemia has been reported as the most prevalent concomitant hematological neoplasm, followed by myelodysplastic, myeloproliferative syndrome, and acute myeloid leukemia; on the other hand, Lymphoproliferative neoplasms were less frequency associated with SM-AHMND. In another
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br Discussion Metastatic RCC is a fatal disease with
2019-06-20
Discussion Metastatic RCC is a fatal disease with survival often measured in months, rather than years. Surgery alone is the standard of care for patients who present with isolated renal disease at the time of diagnosis. However, approximately 1/3 of these patients will go on to develop clinicall
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Several anti platelet therapies have been evaluated in the
2019-06-20
Several anti-platelet therapies have been evaluated in the context of bone metastasis. In vitro, a dual anti-platelet treatment using the soluble ADPase APT102 and an inhibitor of TxA2 synthesis (Aspirin) markedly affected tumor cell-induced platelet aggregation without altering tumor cell viability
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In Telek Ayove and colleagues report
2019-06-20
In , Telek Ayove and colleagues report a comparison of the Dual Path Platform (DPP) Syphilis Screen and Confirm test (Chembio Diagnostic Systems, Medford, NY, USA) with non-treponemal (RPR) and treponemal (TPHA) serological tests for diagnosis of yaws in two remote communities in Papua New Guinea wi
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In our study acute toxicities
2019-06-20
In our study, acute toxicities were mild, and there were no Grade 3 or above hematologic toxicities. Only one patient (3.2%) had Grade 3 esophagus toxicity and three patients (9.7%) had Grade 3 lung toxicity. Compared with studies that investigated regimens of oxaliplatin and 5-FU/leucovorin, the pr
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SQTS is relatively rare but should
2019-06-20
SQTS is relatively rare, but should be considered if the QT interval is markedly abbreviated and the ST segment is nearly absent with peaked and symmetrical T waves. Thus far, mutations in 5 different genes have been found, but genetic testing remains investigational because these genes account for
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Early recognition of ICD lead malfunction is desirable
2019-06-20
Early recognition of ICD lead malfunction is desirable to prevent the life-threatening consequences of lead failure. Recent reports indicate that the majority of patients with ICD lead failure experience inappropriate ICD therapies, often as the presenting problem [4,6]. Regular device interrogation
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The electrophysiological mechanisms underlying high frequenc
2019-06-20
The electrophysiological mechanisms underlying high frequency activity observed in the PLA during SRAF could be reentry (rotor) or focal discharges (triggered activity). To discriminate between these mechanisms, we perfused ryanodine (10–40μM) or caffeine (5mM) to abolish calcium overload-mediated t
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br Ethics br Funding br Conflicts of interest br
2019-06-20
Ethics Funding Conflicts of interest Acknowledgments Case A 68-year-old man with palpitations was referred to our center for catheter ablation because of drug-refractory atrial fibrillation (AF). The preoperative multidetector computed tomography showed a congenital vascular anomaly:
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During a mean of months of
2019-06-20
During a mean of 41±29 months of follow-up, freedom from VT or VF was observed more frequently in the non-inducible group (24 of 30 (75%)) than in the inducible group (9 of 21 (43%), P=0.03). The estimated cumulative freedom from VT or VF was 88%, 83%, 75%, and 55% at the 1-, 2-, 3-, and 5-year foll
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br Conclusions br Disclosures br Funding
2019-06-20
Conclusions Disclosures Funding Sources Introduction Pulmonary vein isolation (PVI) has become an accepted treatment for atrial fibrillation (AF) [1]. The efficacy of PVI is sometimes insufficient, and atrial substrate modification of target specific AF signals indicating the substrate r
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